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Abcam AMN082 Dihydrochloride, mGlu7 Agonist, Solid, 10 mg

Catalog No. 502707944
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50-270-7944 10 mg
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Catalog No. 50-270-7944 Supplier Abcam Supplier No. AB12001110MG
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Description

Potent, selective, orally active, and brain-penetrant mGlu7 receptor agonist.

  • Molecular Weight: 465.5 Da
  • Purity: >98%
  • Form: Solid
  • Activity: Potent, selective, orally active and brain penetrant mGlu7 receptor agonist
  • Experimental Data: Potently inhibits cAMP accumulation and stimulates GTP binding (EC50 = 64–290 nM) in mGluR7 transfected cells; selective over mGlu1, 2, 3, 4, 5, 6, and 8, and ionotropic receptors (up to 10 μM)
  • In Vivo Effects: Elevates plasma stress hormones; induces mGlu7 receptor internalisation in dissociated hippocampal neurones
  • Storage Conditions: Store at +4°C

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Target Molecule mGlu7 Receptor
Form Solid
Shipping Condition Ambient
Buffer 100% AMN082
Content And Storage Store at 4°C.
Quantity 10 mg
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