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AMPD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732536 Shop All Proteintech Group Inc Products
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50-173-2536 150 μL
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Catalog No. 50-173-2536 Supplier Proteintech Group Inc Supplier No. 197801AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to AMPD1.

AMP deaminase (AMPD) is an allosteric enzyme involved in the regulation of adenosine metabolism. It catalyzes a central reaction in purine nucleotide biosynthesis where AMP is deaminated to IMP, liberating ammonia. There are three functional isoforms of AMPD. AMPD1 (E.C. No 3.5.4.6. ) is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. This protein is the predomit member of AMPD multi-gene family and is considered as the sensor of the cell′s changing energy requirements. AMPD1 deficiency causes irregular muscle metabolism due to lower rate of ATP degradation, phosphocreatine hydrolysis and accumulation of lactic acid. Mutated AMPD1 expression has been detected in neuromuscular disorders, exercise-induced skeletal muscle myopathies and congestive heart failures due to coronary artery diseases.

Specifications

Antigen AMPD1
Applications Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AMPD1
Gene Accession No. P10759, P23109, Q3V1D3
Gene Alias AMP deaminase 1, AMP deaminase isoform M, AMPD1, MAD, MADA, Myoadenylate deaminase
Gene Symbols Ampd1
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 229665, 25028, 270
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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