AMPK alpha 2 Polyclonal Antibody, Bethyl Laboratories

Catalog No.
50-155-7787	20 μL; Unconjugated

Catalog No. 50-155-7787 Supplier Bethyl Laboratories, Inc Supplier No. A300508AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Pig and Orangutan

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Specifications

• Antigen: AMPK alpha 2
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene: PRKAA2
• Gene Accession No.: P54646, Q8BRK8
• Gene Alias: 5′-AMP-activated protein kinase, catalytic alpha-2 chain; AMPK alpha-2 chain
• Gene Symbols: PRKAA2
• Host Species: Rabbit
• Immunogen: Between 350 and 400
• Purification Method: Antigen affinity chromatography
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 108079, 5563
• Target Species: Human, Mouse
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG