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AMPK beta 1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

$395.30

Specifications

Antigen AMPK beta 1
Concentration 0.23 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate Unconjugated
Format Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-6197
Encompass_Preferred
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Proteintech Group IncSupplier Diversity Partner
103081AP150UL
150 μL
Each for $395.30
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Description

Description

AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Specifications

Specifications

AMPK beta 1
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.23 mg/mL
Unconjugated
Rabbit
Human, Mouse
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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