AMPK beta 2 Mouse anti-Human, Mouse, Rat, Clone: 2D5C1, Proteintech

Catalog No.	Quantity
50-173-6997	150 μL

Catalog No. 50-173-6997 Supplier Proteintech Group Inc Supplier No. 665791IG150UL

Description

Mouse Monoclonal Antibody

AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

Specifications

• Antigen: AMPK beta 2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 2D5C1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PRKAB2
• Gene Accession No.: O43741, Q6PAM0, Q9QZH4
• Gene Alias: AMPK subunit beta 2, PRKAB2
• Gene Symbols: PRKAB2
• Host Species: Mouse
• Immunogen: AMPK beta 2 Fusion Protein Ag5806
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 108097, 5565, 64562
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1