Invitrogen™ AMPK gamma-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567469

Catalog No. PIPA567469

Description

Immunogen sequence: METVISSDSSP AVENEHPQET PESNNSVYT Highest antigen sequence identity to the following orthologs - mouse 67%, rat 60%.

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Specifications

• Antigen: AMPK gamma-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRKAG1
• Gene Alias: 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AA571379; AMP-activated protein kinase, noncatalytic gamma-1 subunit; ampk gamma; AMPK gamma1; AMPK gamma-1 chain; AMPK subunit gamma-1; AMPKG; BB036179; Prkaac; PRKAG1; Prkga1; Protein kinase AMP-activated gamma; protein kinase AMP-activated non-catalytic subunit gamma 1; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5571
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P54619
• Gene Symbols: PRKAG1
• Immunogen: Recombinant Human AMPK gamma-1. Recombinant protein control fragment (Product #RP-108125).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG