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Invitrogen™ AMPK gamma-2 Polyclonal Antibody
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Catalog No. PIPA522331
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PIPA522331 100 μL
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Catalog No. PIPA522331 Supplier Invitrogen™ Supplier No. PA522331
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, Mouse brain. Predicted reactivity: Mouse (98%), Rat (97%), Chicken (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMPK gamma-2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.96 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene PRKAG2
Gene Accession No. Q91WG5, Q9UGJ0
Gene Alias 2410051C13Rik; 5'-AMP-activated protein kinase subunit gamma-2; 5-AMP-activated protein kinase, gamma-2 subunit; AAKG; AAKG2; adenosine monophosphate-activated protein kinase gamma 2-subunit; AI854673; AMP-activated protein kinase gamma2 subunit; ampk gamma; AMPK gamma 2; AMPK gamma2; AMPK gamma-2 chain; AMPK subunit gamma-2; CMH6; H91620p; OTTHUMP00000211956; PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; WPWS
Gene Symbols PRKAG2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human AMPK gamma 2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108099, 51422
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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