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Invitrogen™ AMPK gamma-3 Polyclonal Antibody
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Catalog No. PIPA517455
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100 μL
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PIPA517455 100 μL
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Catalog No. PIPA517455 Supplier Invitrogen™ Supplier No. PA517455
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMPK gamma-3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene PRKAG3
Gene Accession No. Q9UGI9
Gene Alias 5'-AMP-activated protein kinase subunit gamma-3; 5'-AMP-activated protein kinase, gamma-3 subunit; Amkg3; AMP-activated protein kinase gamma 3 subunit; AMP-activated protein kinase gamma subunit; ampk gamma; AMPK gamma3; AMPK gamma-3 chain; AMPK subunit gamma-3; Ampkg3; AMPKg3L; AMPKg3S; OTTHUMP00000206393; PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit; protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
Gene Symbols PRKAG3
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the sequence of human AMPK.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53632
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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