Angiotensinogen Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-4185	150 μL

Catalog No. 50-173-4185 Supplier Proteintech Group Inc Supplier No. 239721AP150UL

Description

Rabbit Polyclonal Antibody

AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in AGT gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Specifications

• Antigen: Angiotensinogen
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.27 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: AGT
• Gene Accession No.: P01019
• Gene Alias: AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp[1] angiotensin II, Serpin A8, SERPINA8
• Gene Symbols: AGT
• Host Species: Rabbit
• Immunogen: Angiotensinogen Fusion Protein Ag21121
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 183
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG