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AdipoGen ANGPTL8 h pAb IN108

Supplier: AdipoGen AG25B0033C100

Polyclonal Antibody. Recognizes human ANGPTL8 Betatrophin. Source Rabbit. Applications ELISA, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. ANGPTL8 Angiopoietin-like protein 8 RIFL Lipasin Betatrophin is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. ANGPTL8 may also function in inhibition of lipase activity and on serum triglyceride regulation. ANGPTL8 is expressed in the liver and in white and brown adipose tissue of mice. In humans, ANGPTL8 is found to be predominantly expressed in the liver. ANGPTL8 levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. ANGPTL8, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor.
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