Invitrogen™ ANKLE2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109389

Catalog No. PIPA5109389

Description

Immunogen sequence: CRYNVMHVAA KENQASICQL TLDVLENPDF MRLMYPDDDE AMLQKRIRYV VDLYLNTPDK MGYDTPLHFA CKFGNADVVN VLSSHHLIVK NSRNKYDKTP E.

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

Specifications

• Antigen: ANKLE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANKLE2
• Gene Alias: 1110001J12Rik; Ab2-034; AI661024; Ankle2; ankyrin repeat and LEM domain containing 2; ankyrin repeat and LEM domain-containing protein 2; D5Ertd585e; Kiaa0692; LEM domain containing 7; LEM domain-containing protein 4; LEM4; LEMD7; liver regeneration-related protein LRRG057; MCPH16; RGD1310191
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23141, 360829, 71782
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.05 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q6P1H6, Q7TP65, Q86XL3
• Gene Symbols: ANKLE2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-450 of human ANKLE2 (NP_055929.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov