Invitrogen™ Ankyrin B Monoclonal Antibody (2.2)

Catalog No.	Quantity
33-370-0	100 μg

Catalog No. 33-370-0 Supplier Invitrogen™ Supplier No. 333700

Description

Mouse Monoclonal Antibody

Ankyrin B Monoclonal Antibody for Western Blot, ICC/IF, ELISA

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described.

Specifications

• Antigen: Ankyrin B
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 2.2
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene: ANK2
• Gene Accession No.: Q01484, Q8C8R3
• Gene Alias: AI835472; Ank2; ANK-2; Ank3; AnkB; ankyrin 2, brain; ankyrin 2, neuronal; ankyrin 3, epithelial; ankyrin B; ankyrin, brain; ankyrin-2; ankyrin-2, nonerythrocytic; ankyrin-B; AW491075; Brain ankyrin; brank-2; LQT4; Non-erythroid ankyrin
• Gene Symbols: ANK2
• Host Species: Mouse
• Immunogen: Synthetic peptide derived from the human ankyrin B protein.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 109676, 287, 362036
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1