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Invitrogen™ Ankyrin G Monoclonal Antibody (N106/20), APC
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Catalog No. PIMA545540
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Quantity:
100 μg
Catalog No. Quantity
PIMA545540 100 μg
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Catalog No. PIMA545540

Supplier: Invitrogen™ MA545540

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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45540 was sufficient for detection of Ankyrin-G in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects >approximately 200kDa. This antibody was formerly sold as clone S106-20.

Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells. Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ankyrin G
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N106/20
Concentration 1 mg/mL
Conjugate APC
Formulation 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
Gene ANK3
Gene Accession No. G5E8K5, O70511, Q12955
Gene Alias 2900054D09Rik; AI314020; ANK3; ANK-3; AnkG; ankyrin 3; ankyrin 3 (G); ankyrin 3, epithelial; ankyrin 3, node of Ranvier (ankyrin G); ankyrin G; ankyrin-3; Ankyrin-G; brain-specific ankyrin-G; LOW QUALITY PROTEIN: ankyrin-3; MRT37
Gene Symbols ANK3
Host Species Mouse
Immunogen Fusion protein 1000 C-terminal amino acids of human Ankyrin G (also known as ANK-3 or ankyrin-3) encompassing all of Ankyrin G with the exception of Ankyrin repeats (aa 3377-4377).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11735, 288, 361833
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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