Invitrogen™ Annexin A6 Recombinant Rabbit Monoclonal Antibody (K01_1M79)

Catalog No.	Quantity
MA563163	100 μL
MA564622	50 μL

Catalog No. MA563163 Supplier Invitrogen™ Supplier No. MA563163

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: AKPAQGAKYR GSIHDFPGFD PNQDAEALYT AMKGFGSDKE AILDIITSRS NRQRQEVCQS YKSLYGKDLI ADLKYELTGK FERLIVGLMR PPAYCDAKE Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%, Pig - 90%, Cynomolgus monkey - 98%.

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

Specifications

• Antigen: Annexin A6
• Applications: Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: K01_1M79
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4
• Gene: ANXA6
• Gene Accession No.: P08133, P14824, P48037
• Gene Alias: 67 kDa calelectrin; Annexin A6; annexin VI; annexin VI (p68); annexin VI, p68; annexin-6; Anx6; ANXA6; AnxVI; AW107198; Cabm; calcium-binding protein 65/67; calcium-binding protein CATA 65/67; calcium-binding protein p68; calelectrin; calphobindin II; calphobindin-II; Camb; CBP 65/67; CBP68; chromobindin-20; CPB-II; lipocortin VI; p68; p70; Protein III; testis secretory sperm-binding protein Li 198a
• Gene Symbols: ANXA6
• Host Species: Rabbit
• Immunogen: Recombinant protein of human Annexin VI (aa 2-100).
• Purification Method: Protein A/G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11749, 309, 79125
• Target Species: Human, Mouse, Rat
• Content And Storage: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG