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  6. Invitrogen™ Annexin A6 Recombinant Rabbit Monoclonal Antibody (K01_1M82) 

Invitrogen™ Annexin A6 Recombinant Rabbit Monoclonal Antibody (K01_1M82)
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Catalog No. p-200114354
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MA563094 100 μL
MA564553 50 μL
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Catalog No. MA563094 Supplier Invitrogen™ Supplier No. MA563094
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: IRGELSGDFE KLMLAVVKCI RSTPEYFAER LFKAMKGLGT RDNTLIRIMV SRSELDMLDI REIFRTKYEK SLYSMIKNDT SGEYKKTLLK LSGGDDDAAG QFFPEAAQVA YQMWELSAVA RVELKGTVRP ANDFNPDADA KALRKAMKGL GTDEDTIIDI ITHRSNVQRQ QIRQTFKSHF GRDLMTDLKS EISGDLARLI LGLMMPPAHY DAKQLKKAME GAGTDEKALI EILATRTNAE IRAINEAYKE DYHKSLEDAL SSDTSGHFRR ILISLATGHR EEGGENLDQA RE Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%, Pig - 95%, Cynomolgus monkey - 98%.

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
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Specifications

Antigen Annexin A6
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone K01_1M82
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene ANXA6
Gene Accession No. P08133, P14824
Gene Alias 67 kDa calelectrin; Annexin A6; annexin VI; annexin VI (p68); annexin VI, p68; annexin-6; Anx6; ANXA6; AnxVI; AW107198; Cabm; calcium-binding protein 65/67; calcium-binding protein CATA 65/67; calcium-binding protein p68; calelectrin; calphobindin II; calphobindin-II; Camb; CBP 65/67; CBP68; chromobindin-20; CPB-II; lipocortin VI; p68; p70; Protein III; testis secretory sperm-binding protein Li 198a
Gene Symbols ANXA6
Host Species Rabbit
Immunogen Recombinant protein of human Annexin-6 (aa 230-521).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11749, 309
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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