Invitrogen™ ANP32C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537020

Catalog No. PIPA537020

Description

This antibody detects endogenous protein at a molecular weight of 27 kDa. Purity is >95% by SDS-PAGE.

ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.

Specifications

• Antigen: ANP32C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANP32C
• Gene Alias: acidic (leucine-rich) nuclear phosphoprotein 32 family, member C; acidic (leucine-rich) nuclear phosphoprotein 32 family, pseudogene; acidic leucine-rich nuclear phosphoprotein 32 family member C; acidic nuclear phosphoprotein 32 family member C; ANP32C; Anp32cl; Anp32c-ps; Anp32-ps; EG448829; Phosphoprotein 32-related protein 1; pp32 related 1; PP32R1; Tumorigenic protein pp32r1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23520, 448829
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43423
• Gene Symbols: Anp32-ps, ANP32C
• Immunogen: Synthetic peptide corresponding to amino acids 161-206 of human ANP32C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov