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Invitrogen™ ANP32C Polyclonal Antibody
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Catalog No. PIPA537020
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100 μL
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PIPA537020 100 μL
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Catalog No. PIPA537020 Supplier Invitrogen™ Supplier No. PA537020
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 27 kDa. Purity is >95% by SDS-PAGE.

ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ANP32C
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ANP32C
Gene Accession No. O43423
Gene Alias acidic (leucine-rich) nuclear phosphoprotein 32 family, member C; acidic (leucine-rich) nuclear phosphoprotein 32 family, pseudogene; acidic leucine-rich nuclear phosphoprotein 32 family member C; acidic nuclear phosphoprotein 32 family member C; ANP32C; Anp32cl; Anp32c-ps; Anp32-ps; EG448829; Phosphoprotein 32-related protein 1; pp32 related 1; PP32R1; Tumorigenic protein pp32r1
Gene Symbols Anp32-ps, ANP32C
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 161-206 of human ANP32C.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23520, 448829
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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