aminocarboxymuconate semialdehyde decarboxylase, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant ACMSD.
Manufacturer: Abnova Corporation H00130013A01
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 184.108.40.206) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIMSequence: SHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGLERKQFE
|aminocarboxymuconate semialdehyde decarboxylase|
|ACMSD (NP_612199, 179 a.a. ~ 278 a.a) partial recombinant protein with GST tag.|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant ACMSD.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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