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anti-AKT1 Matched Antibody Pair, Abnova

Catalog No. 89017206 Shop All Abnova Corporation Products
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Catalog No. 89-017-206 Supplier Abnova Corporation Supplier No. H00000207AP11
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Description

Includes

Rabbit affinity purified polyclonal anti-AKT1 (100μg); Mouse monoclonal anti-AKT1, IgG2aκ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.

Host Species: Rabbit; Mouse
Species Reactivity: Human

ELISA

Specifications

Antigen AKT1
Applications ELISA
Classification Monoclonal/Polyclonal
Conjugate Unconjugated
Description This antibody pair set comes with matched antibody pair to detect and quantify protein level of human AKT1.
Gene AKT1
Gene Alias AKT/MGC99656/PKB/PKB-ALPHA/PRKBA/RAC/RAC-ALPHA
Gene Symbols AKT1
Host Species Mouse, Rabbit
Purification Method Affinity Purified
Quantity 1 Set
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 207
Includes Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-AKT1 (100 μg) 2. Detection antibody: mouse monoclonal anti-AKT1, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Target Species Human
Content And Storage Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Isotype IgG2a
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