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ATG9A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521043

Catalog No. PIPA521043


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Description

Description

A suggested positive control is mouse heart tissue lysate. PA5-21043 can be used with blocking peptide PEP-1157.

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9A, a multi-spanning membrane protein localizing to the Golgi apparatus and late endosomes, has been proposed to mediate membrane transport to generate autophagosomes. ATG9A has also been implicated as a regulator of STING (stimulator of interferon genes)-mediated innate immune response.
Specifications

Specifications

ATG9A
Polyclonal
Unconjugated
ATG9A
Liquid
ATG9A
An 18 amino acid peptide near the carboxy terminus of human ATG9A.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q7Z3C6, Q68FE2, Q5FWU3
APG9L1, MGD3208, mATG9; APG9 autophagy 9-like 1; APG9-like 1; autophagy 9-like 1 protein; autophagy-related protein 9A
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
245860, 363254, 79065
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