ATG9A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521043
A suggested positive control is mouse heart tissue lysate. PA5-21043 can be used with blocking peptide PEP-1157.Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9A, a multi-spanning membrane protein localizing to the Golgi apparatus and late endosomes, has been proposed to mediate membrane transport to generate autophagosomes. ATG9A has also been implicated as a regulator of STING (stimulator of interferon genes)-mediated innate immune response.
|An 18 amino acid peptide near the carboxy terminus of human ATG9A.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q7Z3C6, Q68FE2, Q5FWU3|
|APG9L1, MGD3208, mATG9; APG9 autophagy 9-like 1; APG9-like 1; autophagy 9-like 1 protein; autophagy-related protein 9A|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|245860, 363254, 79065|
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