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TGR5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523182

Catalog No. PIPA523182


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Description

Description

BG37 is a 330 amino acid novel enzyme with seven transmembrane domains. It belongs to the G protein-coupled receptor (GPCR) superfamily and functions as a cell surface receptor for bile acids. Cells expressing BG37 when treated with bile acids induce the production of intracellular cAMP, activate the MAP kinase signaling pathway, leads to the internalization of the receptor and regulates proglucagon gene expression in enteroendocrine cells. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids that can be targeted to improve metabolic control. It is known to be ubiquitously expressed in most of the tissues.
Specifications

Specifications

TGR5
Polyclonal
whole serum with 0.05% sodium azide
Q8TDU6, Q80SS6, Q80T02
BG37, GPCR19, GPR131, M-BAR, TGR5, G-protein coupled bile acid receptor 1, G-protein coupled bile acid receptor BG37, G-protein coupled receptor GPCR19, hBG37, hGPCR19, membrane bile acid receptor, membrane-type receptor for bile acids
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
GPBAR1
Liquid
GPBAR1
Synthetic peptide (283 GDQRYTAPWRAAAQRC 298) of BG37/TGR5 protein.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
151306, 227289, 338443
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