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Description
The 5E7 monoclonal antibody specifically binds to mouse B lymphocyte-induced maturation protein 1 (Blimp-1). Blimp-1 is a 98 kDa zinc finger-containing protein that is encoded by the Prdm1 gene and functions as a transcriptional repressor. Blimp-1 is essential for regulating the terminal differentiation of activated B cells into plasma cells. In this process, Blimp-1 suppresses genes involved in B cell proliferation, such as Myc and Bcl6 . It controls other genes, such as
The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
Specifications
Specifications
| Antigen | Blimp-1 |
| Applications | Flow Cytometry, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 5.00E+07 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 421 |
| Description | Prdm1; PR domain zinc finger protein 1; Blimp1; PRDI-BF1; ZNFPR1A1 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse Blimp-1 Recombinant Protein |
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