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BLNK (pY84) Mouse, PE, Clone: J117-1278, BD

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BDB558442 50 Tests
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Catalog No. BDB558442 Supplier BD Biosciences Supplier No. 558442
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Description

Mouse Monoclonal Antibody

B cell activation is initiated by crosslinking the B cell receptor, which leads to activation of non-receptor protein tyrosine kinases (PTK), including Btk, Syk, and three Src kinases, Fyn, Lyn, and Blk. Activated PTKs then phosphorylate multiple cellular proteins involved in B lymphocyte signaling. Syk is responsible for the tyrosine phosphorylation of B cell l i g 2, leading to the activation of downstream signaling pathways.

The J117-1278 monoclonal antibody recognizes the phosphorylated Y84 of BLNK.

TRUSTED_SUSTAINABILITY

Specifications

Antigen BLNK (pY84)
Applications Flow Cytometry
Classification Monoclonal
Clone J117-1278
Conjugate PE
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Phosphorylated Human BLNK Peptide
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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