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Casein Kinase Iε Mouse, Unlabeled, Clone: 1, BD

Catalog No. BDB610445 Shop All BD Biosciences Products
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BDB610446 150 μg
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Catalog No. BDB610445 Supplier BD Biosciences Supplier No. 610445
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Description

Mouse Monoclonal Antibody

Casein Kinase I? (CKIε) is a product of a family of proteins involved in the regulation of various cytoplasmic and nuclear processes including DNA replication and repair. CKIε is a 47.3kDa serine/threonine kinase that plays a role similar to previously described CKI isoforms. It phosphorylates known CKI substrates, including a CKI-specific peptide. In addition, it is inhibited by CKI-7, an inhibitor of other CKI isoforms. CKIε contains a core kinase domain of 285 amino acids which is 53-98% identical to other isoforms and is most similiar in structure to CKIδ. Since various human and yeast CKI proteins exhibit both sequence and functional similarities, CKIε may be involved in mammalian DNA metabolism.

Immunofluorescence, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Casein Kinase Iε
Applications Western Blot
Classification Monoclonal
Clone 1
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Casein Kinase Iε aa. 248-414
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Chicken, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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For Research Use Only.

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