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CD102 Rat anti-Mouse, Unlabeled, Clone: 3C4 (MIC2/4), BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 553326

Catalog No. BDB553326


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Description

Description

The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD102
Monoclonal
0.5mg/mL
ICAM-2
Rat
Affinity Purified
RUO
Primary
Store undiluted at 4°C
Flow Cytometry
3C4 (MIC2/4)
Unconjugated
Aqueous buffered solution containing ≤0.09% sodium azide.
Transfected Cell Line
0.5 mg
Immunology
Mouse
IgG2a κ
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