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CD110 Mouse anti-Human, Unlabeled, Clone: 1.78.1, BD

Catalog No. BDB562137 Shop All BD Biosciences Products
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Description

Mouse Monoclonal Antibody

The 1.78.1 monoclonal antibody specifically binds to the human Thrombopoietin Receptor (TPO-R) that is also know as the Myeloproliferative leukemia protein (c-Mpl) or CD110. CD110 is a type I transmembrane protein and a member of the hematopoietin receptor family. It is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage and platelets. CD110 serves as a receptor for thrombopoietin. Upon binding of thrombopoietin to CD110, megakaryocyte proliferation and differentiation is induced and stem cells are protected from apoptosis.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD110
Applications Western Blot
Classification Monoclonal
Clone 1.78.1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description C-MPL; MPL; MPLV; TPOR; Thrombopoietin receptor
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human c-Mpl extracellular domain
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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