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CD11b Mouse anti-Rat, APC, Clone: WT.5, BD

Catalog No. BDB562102 Shop All BD Biosciences Products
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BDB562102 50 μg
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Catalog No. BDB562102 Supplier BD Biosciences Supplier No. 562102
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Description

Mouse Monoclonal Antibody

The WT.5 monoclonal antibody specifically binds to CD11b, the α subunit of Mac-1 found on neutrophils and myeloid cells, but not on lymphocytes. Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi. Neutrophil binding to ICAM-1 is blocked by mAb WT.5.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11b
Applications Flow Cytometry
Classification Monoclonal
Clone WT.5
Concentration 0.2mg/mL
Conjugate APC
Description Itgam; Integrin αM chain; Mac-1 α chain; Integrin beta 2 alpha subunit
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rt neutrophils
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgA κ
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