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Description
The HL3 monoclonal antibody specifically binds to the integrin α x chain of gp150, 95 (CD11c/CD18). CD11c is expressed on dendritic cells, CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and some NK cells. It is upregulated on IEL and lymph-node T cells following in vivo activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.
For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime two or more BD Horizon Brilliant dyes are used in the same experiment. Fluorescent dye interactions may cause staining artifacts which may affect data interpretation. The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions. More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat. No. 563794).
Specifications
Specifications
| Antigen | CD11c |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | HL3 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 605 |
| Description | Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Hamster |
| Immunogen | C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes |
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