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CD121B Mouse anti-Human, Unlabeled, Clone: MNC2, BD

Catalog No. BDB552401 Shop All BD Biosciences Products
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BDB552401 0.5 mg
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Description

Mouse Monoclonal Antibody

CD121b, also known as interleukin-1 receptor type II (IL-1RII), has a significant role in the inflammatory response. Interleukin-1 receptor type II acts as a decoy receptor to regulate prolonged persistence of IL-1 by binding to IL-1 and preventing the formation of signaling complexes. Membrane IL-1 type II receptor forms a 60 kDa soluble IL-1 receptor type II upon proteolytic cleavage from various cell types after activation with secondary, IL-1 induced cytokines. The soluble IL-1 type II receptor consists of 398 amino acids and 29 amino acids within a short cytoplasmic domain. The MNC2 monoclonal antibody reacts with recombinant and native soluble human IL-1 receptor type II.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD121b
Applications ELISA
Classification Monoclonal
Clone MNC2
Concentration 0.5mg/mL
Conjugate Unconjugated
Description IL-1 Receptor Type II, IL-1 RII
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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