CD153 Mouse anti-Human, Unlabeled, Clone: D2-1173, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 550052

Catalog No. BDB550052

Description

Reacts with CD30 ligand (CD153) a 40 kDa type II membrane glycoprotein expressed mainly on activated T cells, as well as on activated macrophages, neutrophils and both normal and malignant B cells. CD30 ligand is a member of the tumor necrosis factor (TNF) superfamily. In addition to TNF, this family also includes lymphotoxin α (LT α ), LT β , CD154, CD95L, CD70, CD134 ligand, CDw137 ligand, and TRAIL. Results of in vitro studies have shown that CD30 mediates a variety of activation and differentiation, or apoptotic signals. Recently, it has been reported that CD30-deficient mice have elevated numbers of thymocytes and show a gross defect in negative but not positive selection during T cell differentiation, suggesting an important role for CD30/CD30L interactions in the deletion of autoreactive T cells.

Specifications

• Antigen: CD153
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: CD30L, CD30 ligand
• Host Species: Mouse
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: D2-1173
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.