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CD153 Mouse anti-Human, Unlabeled, Clone: D2-1173, BD

Catalog No. BDB550052 Shop All BD Biosciences Products
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BDB550052 0.1 mg
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Catalog No. BDB550052 Supplier BD Biosciences Supplier No. 550052
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Description

Mouse Monoclonal Antibody

Reacts with CD30 ligand (CD153) a 40 kDa type II membrane glycoprotein expressed mainly on activated T cells, as well as on activated macrophages, neutrophils and both normal and malignant B cells. CD30 ligand is a member of the tumor necrosis factor (TNF) superfamily. In addition to TNF, this family also includes lymphotoxin α (LT α ), LT β , CD154, CD95L, CD70, CD134 ligand, CDw137 ligand, and TRAIL. Results of in vitro studies have shown that CD30 mediates a variety of activation and differentiation, or apoptotic signals. Recently, it has been reported that CD30-deficient mice have elevated numbers of thymocytes and show a gross defect in negative but not positive selection during T cell differentiation, suggesting an important role for CD30/CD30L interactions in the deletion of autoreactive T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD153
Applications Flow Cytometry
Classification Monoclonal
Clone D2-1173
Concentration 0.5mg/mL
Conjugate Unconjugated
Description CD30L, CD30 ligand
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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