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CD16/CD32 Rat anti-Mouse, Unlabeled, Clone: 2.4G2, BD

Catalog No. BDB553141 Shop All BD Biosciences Products
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Catalog No. BDB553141 Supplier BD Biosciences Supplier No. 553141
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Rat Monoclonal Antibody

The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse Fc γ III and Fc γ II receptors. It has also been reported to bind the Fc γ I receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the Fc γ III and Fc γ II, and possibly Fc γ I, receptors in vitro and in vivo . CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD16/CD32
Applications Blocking Assay, Flow Cytometry
Classification Monoclonal
Clone 2.4G2
Concentration 0.5mg/mL
Conjugate Unconjugated
Description FcγRIII/FcγRII; Fcgr3/Fcgr2
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse BALB/c Macrophage J774 Cell Line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2b κ
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For Research Use Only.

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