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MilliporeSigma™ anti- CD161 (NK1.1) PerCP-Cy5.5, Clone: PK136,
Mouse Monoclonal Antibody
$189.29
Specifications
| Antigen | CD161 (NK1.1) |
|---|---|
| Clone | PK136 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | PerCP-Cyanine5.5 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
MABF1493MI
|
MilliporeSigma™
MABF1493 |
25 μg |
Each of 1 for $189.29
|
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Description
Specifically detects CD161 (NK1.1) Clone: PK136 in Mouse samples, and it is validated for Flow Cytometry
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).Specifications
| CD161 (NK1.1) | |
| Flow Cytometry | |
| PerCP-Cyanine5.5 | |
| Mouse | |
| Inflammation, Immunology | |
| Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2. | |
| Klrb1b, Ly55b, Nkrp1b | |
| IgG2a κ | |
| Purified by size-exclusion chromatography |
| PK136 | |
| Monoclonal | |
| Purified | |
| RUO | |
| Mouse | |
| P27812 | |
| Proprietary immunogen | |
| Primary | |
| 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze |
For Research Use Only
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