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CD184 Rat anti-Mouse, FITC, Clone: 2B11/CXCR4, BD

Catalog No. p-3969083 Shop All BD Biosciences Products
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25 μg
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BDB561735 25 μg
BDB551967 0.1 mg
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Catalog No. BDB561735 Supplier BD Biosciences Supplier No. 561735
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Description

Rat Monoclonal Antibody

The monoclonal antibody 2B11/CXCR4 reacts with the mouse CD184, which is also known as CXC chemokine receptor, CXCR4. CXCR4 (previously known as fusin, LESTR and HUMSTR), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokines, SDF-1/CXCL12. Mouse CXCR4 showed 91% homology at amino acid level with human CXCR4. The CXCR4 is widely expressed by hematopoietic and non hematopoietic cell types including PMN, monocytes, T cells, B cells, CD34+ progenitor cells, endothelial cells, neurons and astrocytes. The human CXCR4 is used by T-tropic HIV-1 as a co-receptor for viral entry. The mouse CXCR4 gene has been mapped to chromosome 1. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Rat
Clone: 2B11/CXCR4
Isotype: IgG2b κ
Species Reactivity: Mouse
Immunogen: GST-NCXCR4 fusion protein

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD184
Applications Flow Cytometry
Classification Monoclonal
Clone 2B11/CXCR4
Concentration 0.5mg/mL
Conjugate FITC
Description CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen GST-NCXCR4 fusion protein
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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For Research Use Only.

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