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CD212 Rat anti-Human, Unlabeled, Clone: 2B6/12 Tests2, BD

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Description

Rat Monoclonal Antibody

Reacts with IL-12R β 2 subunit, one of two subunits of IL-12R β . It is expressed on T cells and NK cells. IL-12R is a glycoprotein member of the hemopoietin receptor superfamily and is related to gp130, the granulocyte-colony stimulating factor (G-CSF) receptor and leukemia inhibitory factor (LIF). Reports indicate that both, IL-12R β 1 (CD212) and IL-12R β 2 subunits together are capable of high affinity binding to IL-12. IL-12 is an immunomodulatory cytokine produced mainly by antigen presenting cells (APC) and plays a role in promoting Th1-type responses and cell mediated immunity. It stimulates proliferation of T cells and NK cells, enhances lytic activity of lymphokine activated (LAK) cells and CTL.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD212
Applications Flow Cytometry
Classification Monoclonal
Clone 2B6/12 Tests2
Concentration 0.5mg/mL
Conjugate Unconjugated
Description IL-12 receptor subunit beta-2; Interleukin-12 receptor beta-2 chain
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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