CD249 Mouse anti-Human, PE, Clone: 2D3/APA, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564533
The 2D3 monoclonal antibody specifically binds to CD249. CD249 is encoded by ENPEP and is also known as Aminopeptidase A (APA/AP-A), Glutamyl aminopeptidase (EAP), and gp160. CD249 is expressed by epithelial and endothelial cells in a variety of tissues including those that comprise the proximal tubules and glomeruli of the kidneys. It is also expressed by early B-lineage cells and cell lines. CD249 belongs to the peptidase M1 family and catalyzes the release of N-terminal glutamate (and to a lesser degree, aspartate) from peptides. This ectoenzyme catalyzes the conversion of angiotensin II to angiotensin III which is important in the local regulation of blood pressure. It may also play roles in the regulation of angiogenesis and development of B cells.
|EAP, Aminopeptidase A, Glutamyl aminopeptidase, APA, AP-A, gp160, ENPEP|
|Human Aminopeptidase A Transfected Cell Line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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