CD249 Mouse anti-Human, PE, Clone: 2D3/APA, BD

Catalog No.	Quantity
BDB564533	50 Tests

Catalog No. BDB564533 Supplier BD Biosciences Supplier No. 564533

Description

Mouse Monoclonal Antibody

The 2D3 monoclonal antibody specifically binds to CD249. CD249 is encoded by ENPEP and is also known as Aminopeptidase A (APA/AP-A), Glutamyl aminopeptidase (EAP), and gp160. CD249 is expressed by epithelial and endothelial cells in a variety of tissues including those that comprise the proximal tubules and glomeruli of the kidneys. It is also expressed by early B-lineage cells and cell lines. CD249 belongs to the peptidase M1 family and catalyzes the release of N-terminal glutamate (and to a lesser degree, aspartate) from peptides. This ectoenzyme catalyzes the conversion of angiotensin II to angiotensin III which is important in the local regulation of blood pressure. It may also play roles in the regulation of angiogenesis and development of B cells.

Specifications

• Antigen: CD249
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: 2D3/APA
• Conjugate: PE
• Description: EAP, Aminopeptidase A, Glutamyl aminopeptidase, APA, AP-A, gp160, ENPEP
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Mouse
• Immunogen: Human Aminopeptidase A Transfected Cell Line
• Purification Method: Affinity Purified
• Quantity: 50 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG1 κ