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CD249 Mouse anti-Human, PE, Clone: 2D3/APA, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564533

Catalog No. BDB564533


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Description

Description

The 2D3 monoclonal antibody specifically binds to CD249. CD249 is encoded by ENPEP and is also known as Aminopeptidase A (APA/AP-A), Glutamyl aminopeptidase (EAP), and gp160. CD249 is expressed by epithelial and endothelial cells in a variety of tissues including those that comprise the proximal tubules and glomeruli of the kidneys. It is also expressed by early B-lineage cells and cell lines. CD249 belongs to the peptidase M1 family and catalyzes the release of N-terminal glutamate (and to a lesser degree, aspartate) from peptides. This ectoenzyme catalyzes the conversion of angiotensin II to angiotensin III which is important in the local regulation of blood pressure. It may also play roles in the regulation of angiogenesis and development of B cells.

Specifications

Specifications

CD249
2D3/APA
EAP, Aminopeptidase A, Glutamyl aminopeptidase, APA, AP-A, gp160, ENPEP
Affinity Purified
Human Aminopeptidase A Transfected Cell Line
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Human
Flow Cytometry
PE
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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