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Description
Reacts with CD25, a 55kDa glycoprotein known as the low-affinity interleukin-2 receptor (IL-2R). CD25 is expressed on activated lymphocytes (T and B) and monocytes, and associates with the p75 high-affinity receptor chain to form the IL-2R complex. The CD25 molecule reveals three epitope regions: A, B, and C. M-A251 antibody recognizes epitope region B. CD25 expression on lymphocytes is upregulated by anti-CD3 or PHA stimulation. Soluble IL-2R is produced following inflammatory responses. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
Specifications
| Antigen | CD25 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | M-A251 |
| Concentration | 0.5mg/mL |
| Conjugate | Unconjugated |
| Description | IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
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For Research Use Only.
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