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Description
The WM53 monoclonal antibody specifically binds to human CD33. CD33 is a 67 kDa type I transmembrane glycoprotein. It is expressed on monocytes, activated T cells, myeloid progenitors, mast cells and weakly on polymorphonuclear cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes, and hematopoietic stem cells. Reports indicate that this glycoprotein can function as a sialic acid-dependent cell adhesion molecule and this function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane.
Specifications
Specifications
| Antigen | CD33 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | WM53 |
| Conjugate | PE-Cyanine5 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Acute Myeloid Leukemia Blasts |
| Purification Method | Affinity Purified |
| Quantity | 100 Tests |
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For Research Use Only.
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