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Description
The 90 monoclonal antibody specifically binds to CD38, a 42 kDa transmembrane glycoprotein on immature and mature, resting and activated, B lymphocytes. In contrast to humans, CD38 expression is down-regulated on mouse germinal center B cells and plasma cells. CD38 is also expressed on a subpopulation of thymic and peripheral T cells, NK cells, and splenic macrophages. Furthermore, CD38 has been detected on bone marrow-derived hematopoietic stem cells. The CD38 molecule is reported to exhibit both cyclase and hydrolase activities and plays a role in lymphocyte activation. CD31, both human and mouse, is reported to be a ligand for human CD38.
Specifications
Specifications
| Antigen | CD38 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 90 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse Bone Marrow Pre-B cells |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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