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CD42d Mouse anti-Rat, FITC, Clone: RPM.4, BD

Catalog No. BDB551805 Shop All BD Biosciences Products
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BDB551805 0.1 mg
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Description

Mouse Monoclonal Antibody

The RPM.4 antibody reacts with CD42d (Platelet glycoprotein V, GPV), an 88-kDa glycoprotein which noncovalently associates with GPIb and GPIX to form a receptor for von Willebrand factor on megakaryocytes and resting platelets. The binding sites for von Willebrand factor and thrombin have been localized to the GPIbα chain of the GPI-b-V-IX complex. GPV is cleaved by thrombin to release a 70 kDa soluble fragment, which contains the epitope recognized by mAb RPM.4. Although the rat CD42d protein's structure is similar to that of human CD42d, the RPM.4 antibody does not cross-react with human platelets.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD42d
Applications Flow Cytometry
Classification Monoclonal
Clone RPM.4
Concentration 0.5mg/mL
Conjugate FITC
Description Platelet Glycoprotein V
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Wistar rat platelets
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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