CD42d Mouse anti-Rat, FITC, Clone: RPM.4, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 551805

Catalog No. BDB551805

Description

The RPM.4 antibody reacts with CD42d (Platelet glycoprotein V, GPV), an 88-kDa glycoprotein which noncovalently associates with GPIb and GPIX to form a receptor for von Willebrand factor on megakaryocytes and resting platelets. The binding sites for von Willebrand factor and thrombin have been localized to the GPIbα chain of the GPI-b-V-IX complex. GPV is cleaved by thrombin to release a 70 kDa soluble fragment, which contains the epitope recognized by mAb RPM.4. Although the rat CD42d protein's structure is similar to that of human CD42d, the RPM.4 antibody does not cross-react with human platelets.

Specifications

• Antigen: CD42d
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: Platelet Glycoprotein V
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: RPM.4
• Conjugate: FITC
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Wistar rat platelets
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Rat
• Isotype: IgG2a κ

For Research Use Only.