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CD45 Mouse anti-Rat, APC-Cy7, Clone: OX-1, BD

Catalog No. BDB561586 Shop All BD Biosciences Products
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BDB561586 50 μg
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Catalog No. BDB561586 Supplier BD Biosciences Supplier No. 561586
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Description

Mouse Monoclonal Antibody

The OX-1 antibody recognizes all molecular forms of CD45 (Leukocyte Common Antigen) on all hematopoietic cells except erythrocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family; its intracellular (COOH-terminal) region contains two PTP catalytic domains while the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), and differing levels of glycosylation. The CD45 isoforms detected in rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD45
Applications Flow Cytometry
Classification Monoclonal
Clone OX-1
Concentration 0.2mg/mL
Conjugate APC-Cyanine7
Description Ptprc; Lca; Leucocyte common antigen; RT7; T200
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Leukocyte Common Antigen-enriched Glycoprotein Fraction from Wistar Rat Thymocytes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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