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CD47 Mouse anti-Human, NA/LE, Unlabeled, Clone: B6H12, BD

Catalog No. BDB556043 Shop All BD Biosciences Products
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Catalog No. BDB556043 Supplier BD Biosciences Supplier No. 556043
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Description

Mouse Monoclonal Antibody

Reacts with a 42-52kDa N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD47
Applications Flow Cytometry
Classification Monoclonal
Clone B6H12
Concentration 1.0mg/mL
Conjugate Unconjugated
Description IAP; CDw149; gp42; MER6; Neurophilin; OA3 ; Rh-related antigen
Formulation No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species Mouse
Immunogen Purified human placental RGD-binding proteins
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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