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CD51/CD61 Mouse anti-Human, Unlabeled, Clone: 23C6, BD

Catalog No. BDB555504 Shop All BD Biosciences Products
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Description

Mouse Monoclonal Antibody

The 23C6 monoclonal antibody specifically binds to the Integrin αvβ3 heterodimeric complex (CD51/CD61) that is expressed on osteoclasts, endothelial cells, macrophages, melanoma cells, some B cells and in very low amounts on platelets. This antibody has been reported to crossreact with chicken and rabbit, but not with rat αvβ3. The integrin αvβ3 heterodimer, often referred to as the vitronectin receptor, binds several ligands in addition to vitronectin including, von Willebrand factor, thrombospondin, osteopontin, bone sialoprotein, neural adhesion molecule L1, laminin, fibronectin, and fibrinogen. The binding of some ligands to the vitronectin receptor has been reported to be inhibited by the 23C6 monoclonal antibody.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD51/CD61
Applications Flow Cytometry
Classification Monoclonal
Clone 23C6
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human, Rabbit
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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