CD81 Mouse anti-Human, Unlabeled, Clone: JS-81, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555675

Catalog No. BDB555675

Description

JS-81 identifies the newly clustered CD81 antigen, a 26kDa, type III transmembrane protein (also known as TAPA-1) that is involved in cell growth and signal transduction. CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. MAbs to CD81 have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Immunoprecipitation studies reveal that CD81 is a component of a multimolecular complex which can include the Leu13 molecule, and the CD19 and CD21 molecules in B cells. MAbs to CD81 are reported to induce homotypic cell aggregation.

Host Species: Mouse
Clone: JS-81
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD81
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: TAPA-1
• Host Species: Mouse
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Canine, Human, Rabbit
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: JS-81
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.