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CDX-2 Mouse anti-Human, PE, Clone: M39-71, BD

Catalog No. BDB563428 Shop All BD Biosciences Products
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BDB563428 50 Tests
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Catalog No. BDB563428 Supplier BD Biosciences Supplier No. 563428
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Description

Mouse Monoclonal Antibody

The M39-711 monoclonal antibody reacts with caudal-type homeobox transcription factor 2 (CDX-2). In embryonic development, CDX-2 is first expressed in the outer layer of the morula and later in the trophoblast, but not in embryonic stem cells. Along with Oct3/4, it is involved in the segregation of the trophoectoderm lineage from the inner cell mass. In the adult, CDX-2 expression is limited to the mucosa of the small and large intestines, where it regulates the synthesis of several intestine-specific proteins. Loss of CDX-2 expression is observed in some colorectal carcinomas, while gain of CDX-2 expression has been observed in gastric tumors and acute myeloid leukemias.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CDX-2
Applications Flow Cytometry
Classification Monoclonal
Clone M39-71
Conjugate PE
Description CDX2, CDX3, CDX-3
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human CDX-2 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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