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Clec9A (CD370) Rat anti-Human, PE, Clone: 3A4/Clec9A (also known as 20/05-3A4 or 3A4), BD

Catalog No. BDB563488 Shop All BD Biosciences Products
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BDB563488 25 μg
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Catalog No. BDB563488 Supplier BD Biosciences Supplier No. 563488
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Description

Rat Monoclonal Antibody

The 3A4/Clec9A monoclonal antibody specifically binds to human Clec9A (C-type lectin domain family member 9A). Clec9A is a type II transmembrane glycoprotein with a single extracellular C-type lectin domain. Clec9A is also known as CD370 and DNGR1 (Dendritic cell natural killer lectin group receptor 1). Clec9A is selectively expressed on CD141+ myeloid dendritic cells. Clec9A reportedly functions as an endocytic receptor for necrotic cells. It can mediate the cross-presentation of dead-cell associated antigens by dendritic cells in a Syk-dependent manner. The 3A4 antibody reportedly crossreacts with peripheral blood dendritic cells form Pigtail macaques ( Macaca nemestrina ).

TRUSTED_SUSTAINABILITY

Specifications

Antigen Clec9A (CD370)
Applications Flow Cytometry
Classification Monoclonal
Clone 3A4/Clec9A (also known as 20/05-3A4 or 3A4)
Concentration 0.2mg/mL
Conjugate PE
Description CD370; C-type lectin domain family 9 member A; CLEC9A; DNGR1
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Human Clec9A Peptide
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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