Clec9A (CD370) Rat anti-Human, PE, Clone: 3A4/Clec9A (also known as 20/05-3A4 or 3A4), BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 563488
The 3A4/Clec9A monoclonal antibody specifically binds to human Clec9A (C-type lectin domain family member 9A). Clec9A is a type II transmembrane glycoprotein with a single extracellular C-type lectin domain. Clec9A is also known as CD370 and DNGR1 (Dendritic cell natural killer lectin group receptor 1). Clec9A is selectively expressed on CD141+ myeloid dendritic cells. Clec9A reportedly functions as an endocytic receptor for necrotic cells. It can mediate the cross-presentation of dead-cell associated antigens by dendritic cells in a Syk-dependent manner. The 3A4 antibody reportedly crossreacts with peripheral blood dendritic cells form Pigtail macaques ( Macaca nemestrina ).
|3A4/Clec9A (also known as 20/05-3A4 or 3A4)|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|IgG2a, κ, also known as Wistar (outbred) IgG2a, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|CD370; C-type lectin domain family 9 member A; CLEC9A; DNGR1|
|Human Clec9A Peptide|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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