Clec9A (CD370) Rat anti-Human, PE, Clone: 3A4/Clec9A (also known as 20/05-3A4 or 3A4), BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 563488

Catalog No. BDB563488

Description

The 3A4/Clec9A monoclonal antibody specifically binds to human Clec9A (C-type lectin domain family member 9A). Clec9A is a type II transmembrane glycoprotein with a single extracellular C-type lectin domain. Clec9A is also known as CD370 and DNGR1 (Dendritic cell natural killer lectin group receptor 1). Clec9A is selectively expressed on CD141+ myeloid dendritic cells. Clec9A reportedly functions as an endocytic receptor for necrotic cells. It can mediate the cross-presentation of dead-cell associated antigens by dendritic cells in a Syk-dependent manner. The 3A4 antibody reportedly crossreacts with peripheral blood dendritic cells form Pigtail macaques ( Macaca nemestrina ).

Specifications

• Antigen: Clec9A (CD370)
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: CD370; C-type lectin domain family 9 member A; CLEC9A; DNGR1
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human, Monkey
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: 3A4/Clec9A (also known as 20/05-3A4 or 3A4)
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human Clec9A Peptide
• Quantity: 25 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.