anti-COMT Matched Antibody Pair, Ab-1, Abnova

Catalog No.	Quantity
89-017-249	1 Set

Catalog No. 89-017-249 Supplier Abnova Corporation Supplier No. H00001312AP11

Description

Includes

Rabbit MaxPab™ affinity purified polyclonal anti-COMT (100μg); Mouse monoclonal anti-COMT, IgG2bκ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

ELISA

Specifications

• Antigen: COMT
• Applications: ELISA
• Classification: Monoclonal/Polyclonal
• Conjugate: Unconjugated
• Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human COMT.
• Gene: COMT
• Gene Symbols: COMT
• Host Species: Mouse, Rabbit
• Purification Method: Affinity Purified
• Quantity: 1 Set
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1312
• Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-COMT (100 μg) 2. Detection antibody: mouse monoclonal anti-COMT, IgG2b Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
• Target Species: Human
• Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
• Isotype: IgG2b