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Thermo Scientific™ Lab Vision™ COX2, Rabbit Monoclonal Antibody
Obtain accurate, reproducible results in Immunohistochemistry experiments with Thermo Scientific™ COX2, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio.
Manufacturer: Thermo Scientific™ RM9121R7
Description
Obtain accurate, reproducible results in Immunohistochemistry experiments with Thermo Scientific™ COX2, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.
COX2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate-early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.Host Species: Rabbit
Clone: SP21
Isotype: IgG
Species Reactivity: Human, Mouse and Rat. Others not tested.
Epitope: C-terminus
Immunogen: A synthetic peptide from C-terminus of rat COX2
Molecular Weight: 70 kDa
Positive Control: Lung and colon CAs
Cellular Localization: Cytoplasmic and membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Specifications
| COX2 | |
| Monoclonal | |
| Unconjugated | |
| Rabbit | |
| IgG | |
| IVD | |
| Primary | |
| Monoclonal |
| Immunohistochemistry (Paraffin) | |
| SP21 | |
| Prediluted | |
| A synthetic peptide from C-terminus of rat cox2 | |
| 7mL | |
| Enzyme | |
| Primary | |
| Human, Murine |
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