DHCR24, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human DHCR24 peptide using ARM Technology.

Supplier:  Abnova Corporation H00001718K

Catalog No. 89-205-097

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: DHCR24
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: DHCR24
• Gene Symbols: DHCR24
• Immunogen: A synthetic peptide of human DHCR24
• Regulatory Status: RUO
• Gene ID (Entrez): 1718
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: 24-dehydrocholesterol reductase
• Gene: DHCR24
• Gene Alias: KIAA0018, Nbla03646, SELADIN1, seladin-1
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid