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Description
Includes
Rabbit MaxPab™ affinity purified polyclonal anti-EDN3 (100μg); Mouse monoclonal anti-EDN3, IgG1κ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
ELISA
Specifications
Specifications
| Antigen | EDN3 |
| Applications | ELISA |
| Classification | Monoclonal/Polyclonal |
| Conjugate | Unconjugated |
| Description | This antibody pair set comes with matched antibody pair to detect and quantify protein level of human EDN3. |
| Gene | EDN3 |
| Gene Alias | ET3/MGC15067/MGC61498 |
| Gene Symbols | EDN3 |
| Host Species | Mouse, Rabbit |
| Purification Method | Affinity Purified |
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