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EGF Receptor Mouse anti-Human, Alexa Fluor 647, Clone: EGFR.1, BD

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BDB563577 50 Tests
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Catalog No. BDB563577 Supplier BD Biosciences Supplier No. 563577
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Description

Mouse Monoclonal Antibody

The EGFR.1 monoclonal antibody specifically binds to the epidermal growth factor receptor (EGF-R). The EGF-R is a transmembrane glycoprotein ofapproximately 170 kDa that is expressed on most cells. It consists of a glycosylated extracellular domain which binds to epidermal growth factor (EGF), a transmembrane domain, and an intracellular domain with tyrosine-kinase activity essential for signal transduction. The EGF-R plays an important role in the growth and differentiation of many cellular types. Transforming growth factor α (TGFα), vaccinia virus growth factor, and related growth factors can also bind to and signal through the EGF-R.

TRUSTED_SUSTAINABILITY

Specifications

Antigen EGF Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone EGFR.1
Conjugate Alexa Fluor 647
Description EGFR; ERBB; ERBB1; HER1; mENA; PIG61
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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