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Description
The Avas 12α1 antibody reacts with fetal liver kinase 1 (Flk-1), a receptor protein tyrosine kinase closely related to CD117 (c-kit) and CD140a (PDGF Receptor α chain) of the immunoglobulin superfamily. Flk-1, also known as VEGF Receptor-2 (VEGF-R2), is a receptor for vascular endothelial growth factor (VEGF). It is expressed, at the mRNA and protein levels, on distinct sets of mesoderm during gastrulation and on endothelial cells in embryonic tissues. In vivo and in vitro studies indicate that Flk-1 is required for the embryonic development of vascular endothelial and hematopoietic cells.
Flow Cytometry, Intracellular Staining
Specifications
Specifications
| Antigen | Flk-1 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | AVAS 12A1 |
| Concentration | 0.2mg/mL |
| Conjugate | PerCP-Cyanine5.5 |
| Description | Fetal liver kinase 1; CD309; Kdr; VEGF receptor-2; VEGFR-2 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse Flk1 and human IgG1 fusion protein |
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